Reversible block of mouse neural stem cell differentiation in the absence of dicer and microRNAs
Reversible block of mouse neural stem cell differentiation in the absence of dicer and microRNAs
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
To investigate the functions of Dicer and microRNAs in neural stem (NS) cell self-renewal and neurogenesis, we established neural stem cell lines from the embryonic mouse Dicer-null cerebral cortex, producing neural stem cell lines that lacked all microRNAs.
Dicer-null NS cells underwent normal self-renewal and could be maintained in vitro indef...
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Full title
Reversible block of mouse neural stem cell differentiation in the absence of dicer and microRNAs
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TN_cdi_plos_journals_1292840952
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292840952
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0013453
