Effect of population heterogenization on the reproducibility of mouse behavior: a multi-laboratory s...
Effect of population heterogenization on the reproducibility of mouse behavior: a multi-laboratory study
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Author / Creator
Richter, S Helene , Garner, Joseph P , Zipser, Benjamin , Lewejohann, Lars , Sachser, Norbert , Touma, Chadi , Schindler, Britta , Chourbaji, Sabine , Brandwein, Christiane , Gass, Peter , van Stipdonk, Niek , van der Harst, Johanneke , Spruijt, Berry , Võikar, Vootele , Wolfer, David P and Würbel, Hanno
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Contents
In animal experiments, animals, husbandry and test procedures are traditionally standardized to maximize test sensitivity and minimize animal use, assuming that this will also guarantee reproducibility. However, by reducing within-experiment variation, standardization may limit inference to the specific experimental conditions. Indeed, we have rece...
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Full title
Effect of population heterogenization on the reproducibility of mouse behavior: a multi-laboratory study
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Record Identifier
TN_cdi_plos_journals_1293664608
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1293664608
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0016461
