Benchmarking of Mutation Diagnostics in Clinical Lung Cancer Specimens
Benchmarking of Mutation Diagnostics in Clinical Lung Cancer Specimens
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Author / Creator
Querings, Silvia , Altmüller, Janine , Ansén, Sascha , Zander, Thomas , Seidel, Danila , Gabler, Franziska , Peifer, Martin , Markert, Eva , Stemshorn, Kathryn , Timmermann, Bernd , Saal, Beate , Klose, Stefan , Ernestus, Karen , Scheffler, Matthias , Engel-Riedel, Walburga , Stoelben, Erich , Brambilla, Elisabeth , Wolf, Jürgen , Nürnberg, Peter and Thomas, Roman K.
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
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More information
Scope and Contents
Contents
Treatment of EGFR-mutant non-small cell lung cancer patients with the tyrosine kinase inhibitors erlotinib or gefitinib results in high response rates and prolonged progression-free survival. Despite the development of sensitive mutation detection approaches, a thorough validation of these in a clinical setting has so far been lacking. We performed...
Alternative Titles
Full title
Benchmarking of Mutation Diagnostics in Clinical Lung Cancer Specimens
Authors, Artists and Contributors
Author / Creator
Altmüller, Janine
Ansén, Sascha
Zander, Thomas
Seidel, Danila
Gabler, Franziska
Peifer, Martin
Markert, Eva
Stemshorn, Kathryn
Timmermann, Bernd
Saal, Beate
Klose, Stefan
Ernestus, Karen
Scheffler, Matthias
Engel-Riedel, Walburga
Stoelben, Erich
Brambilla, Elisabeth
Wolf, Jürgen
Nürnberg, Peter
Thomas, Roman K.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1294916018
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1294916018
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0019601