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Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) leve...

Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) leve...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1294954764

Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans

About this item

Full title

Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011-01, Vol.6 (1), p.e14581

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Lipoprotein(a) (Lp(a)) is an important causal cardiovascular risk factor, with serum Lp(a) levels predicting atherosclerotic heart disease and genetic determinants of Lp(a) levels showing association with myocardial infarction. Lp(a) levels vary widely between populations, with African-derived populations having nearly 2-fold higher Lp(a) levels th...

Alternative Titles

Full title

Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1294954764

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1294954764

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0014581

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