Phase I safety and immunogenicity evaluation of MVA-CMDR, a multigenic, recombinant modified vaccini...
Phase I safety and immunogenicity evaluation of MVA-CMDR, a multigenic, recombinant modified vaccinia Ankara-HIV-1 vaccine candidate
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Author / Creator
Currier, Jeffrey R , Ngauy, Viseth , de Souza, Mark S , Ratto-Kim, Silvia , Cox, Josephine H , Polonis, Victoria R , Earl, Patricia , Moss, Bernard , Peel, Sheila , Slike, Bonnie , Sriplienchan, Somchai , Thongcharoen, Prasert , Paris, Robert M , Robb, Merlin L , Kim, Jerome , Michael, Nelson L and Marovich, Mary A
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
We conducted a Phase I randomized, dose-escalation, route-comparison trial of MVA-CMDR, a candidate HIV-1 vaccine based on a recombinant modified vaccinia Ankara viral vector expressing HIV-1 genes env/gag/pol. The HIV sequences were derived from circulating recombinant form CRF01_AE, which predominates in Thailand. The objective was to evaluate sa...
Alternative Titles
Full title
Phase I safety and immunogenicity evaluation of MVA-CMDR, a multigenic, recombinant modified vaccinia Ankara-HIV-1 vaccine candidate
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Record Identifier
TN_cdi_plos_journals_1295201632
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1295201632
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0013983
