MYC cooperates with AKT in prostate tumorigenesis and alters sensitivity to mTOR inhibitors
MYC cooperates with AKT in prostate tumorigenesis and alters sensitivity to mTOR inhibitors
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
MYC and phosphoinositide 3-kinase (PI3K)-pathway deregulation are common in human prostate cancer. Through examination of 194 human prostate tumors, we observed statistically significant co-occurrence of MYC amplification and PI3K-pathway alteration, raising the possibility that these two lesions cooperate in prostate cancer progression. To investi...
Alternative Titles
Full title
MYC cooperates with AKT in prostate tumorigenesis and alters sensitivity to mTOR inhibitors
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1295591776
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1295591776
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0017449
