Plasmin inhibitors prevent leukocyte accumulation and remodeling events in the postischemic microvas...
Plasmin inhibitors prevent leukocyte accumulation and remodeling events in the postischemic microvasculature
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Clinical trials revealed beneficial effects of the broad-spectrum serine protease inhibitor aprotinin on the prevention of ischemia-reperfusion (I/R) injury. The underlying mechanisms remained largely unclear. Using in vivo microscopy on the cremaster muscle of male C57BL/6 mice, aprotinin as well as inhibitors of the serine protease plasmin includ...
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Full title
Plasmin inhibitors prevent leukocyte accumulation and remodeling events in the postischemic microvasculature
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TN_cdi_plos_journals_1296304824
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1296304824
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0017229