Tumor-associated macrophages recruit CCR6+ regulatory T cells and promote the development of colorec...
Tumor-associated macrophages recruit CCR6+ regulatory T cells and promote the development of colorectal cancer via enhancing CCL20 production in mice
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Author / Creator
Liu, Jinlin , Zhang, Ning , Li, Qun , Zhang, Weiwei , Ke, Fang , Leng, Qibin , Wang, Hong , Chen, Jinfei and Wang, Honglin
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Contents
Tumor-associated macrophages (TAMs) remodel the colorectal cancer (CRC) microenvironment. Yet, findings on the role of TAMs in CRC seem to be contradictory compared with other cancers. FoxP3(+) regulatory T (Treg)-cells dominantly infiltrate CRC. However, the underlying molecular mechanism in which TAMs may contribute to the trafficking of Treg-cel...
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Full title
Tumor-associated macrophages recruit CCR6+ regulatory T cells and promote the development of colorectal cancer via enhancing CCL20 production in mice
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TN_cdi_plos_journals_1296542340
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1296542340
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0019495
