A cyclic undecamer peptide mimics a turn in folded Alzheimer amyloid β and elicits antibodies agains...
A cyclic undecamer peptide mimics a turn in folded Alzheimer amyloid β and elicits antibodies against oligomeric and fibrillar amyloid and plaques
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The 39- to 42-residue amyloid β (Aβ) peptide is deposited in extracellular fibrillar plaques in the brain of patients suffering from Alzheimer's Disease (AD). Vaccination with these peptides seems to be a promising approach to reduce the plaque load but results in a dominant antibody response directed against the N-terminus. Antibodies against the...
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Full title
A cyclic undecamer peptide mimics a turn in folded Alzheimer amyloid β and elicits antibodies against oligomeric and fibrillar amyloid and plaques
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TN_cdi_plos_journals_1296761236
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1296761236
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0019110
