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Nucleolar localization of RNA binding proteins induced by actinomycin D and heat shock in Trypanosom...

Nucleolar localization of RNA binding proteins induced by actinomycin D and heat shock in Trypanosom...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1298575957

Nucleolar localization of RNA binding proteins induced by actinomycin D and heat shock in Trypanosoma cruzi

About this item

Full title

Nucleolar localization of RNA binding proteins induced by actinomycin D and heat shock in Trypanosoma cruzi

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011-05, Vol.6 (5), p.e19920-e19920

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

In this work we show that under Actinomycin D (ActD) treatment, several RNA Binding Proteins (RBPs) involved in mRNA metabolism are relocalized into the nucleolus in Trypanosoma cruzi as a specific stress response. ATP depletion as well as kinase inhibition markedly reduced the nucleolar localization response, suggesting that an energy-dependent tr...

Alternative Titles

Full title

Nucleolar localization of RNA binding proteins induced by actinomycin D and heat shock in Trypanosoma cruzi

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1298575957

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1298575957

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0019920

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