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Mesenchymal transition and dissemination of cancer cells is driven by myeloid-derived suppressor cel...

Mesenchymal transition and dissemination of cancer cells is driven by myeloid-derived suppressor cel...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1298577075

Mesenchymal transition and dissemination of cancer cells is driven by myeloid-derived suppressor cells infiltrating the primary tumor

About this item

Full title

Mesenchymal transition and dissemination of cancer cells is driven by myeloid-derived suppressor cells infiltrating the primary tumor

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2011-09, Vol.9 (9), p.e1001162-e1001162

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

In order to metastasize, cancer cells need to acquire a motile phenotype. Previously, development of this phenotype was thought to rely on the acquisition of selected, random mutations and thus would occur late in cancer progression. However, recent studies show that cancer cells disseminate early, implying the existence of a different, faster rout...

Alternative Titles

Full title

Mesenchymal transition and dissemination of cancer cells is driven by myeloid-derived suppressor cells infiltrating the primary tumor

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1298577075

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1298577075

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.1001162

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