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ELF5 Suppresses Estrogen Sensitivity and Underpins the Acquisition of Antiestrogen Resistance in Lum...

ELF5 Suppresses Estrogen Sensitivity and Underpins the Acquisition of Antiestrogen Resistance in Lum...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1304036617

ELF5 Suppresses Estrogen Sensitivity and Underpins the Acquisition of Antiestrogen Resistance in Luminal Breast Cancer

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

We have previously shown that during pregnancy the E-twenty-six (ETS) transcription factor ELF5 directs the differentiation of mammary progenitor cells toward the estrogen receptor (ER)-negative and milk producing cell lineage, raising the possibility that ELF5 may suppress the estrogen sensitivity of breast cancers. To test this we constructed ind...

Alternative Titles

Full title

ELF5 Suppresses Estrogen Sensitivity and Underpins the Acquisition of Antiestrogen Resistance in Luminal Breast Cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1304036617

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1304036617

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.1001461

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