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Myeloid-Derived Suppressor Cells as a Therapeutic Target for Cancer
Author / Creator:Law, Andrew M. K. ; Valdes-Mora, Fatima ; Gallego-Ortega, David
Publisher:Switzerland: MDPI
Journal title:Cells (Basel, Switzerland), 2020-02, Vol.9 (3), p.561
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Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis
Author / Creator:Papanicolaou, Michael ; Parker, Amelia L. ; Yam, Michelle ; Filipe, Elysse C. ; Wu, Sunny Z. ; Chitty, Jessica L. ; Wyllie, Kaitlin ; Tran, Emmi ; Mok, Ellie ; Nadalini, Audrey ; Skhinas, Joanna N. ; Lucas, Morghan C. ; Herrmann, David ; Nobis, Max ; Pereira, Brooke A. ; Law, Andrew M. K. ; Castillo, Lesley ; Murphy, Kendelle J. ; Zaratzian, Anaiis ; Hastings, Jordan F. ; Croucher, David R. ; Lim, Elgene ; Oliver, Brian G. ; Mora, Fatima Valdes ; Parker, Benjamin L. ; Gallego-Ortega, David ; Swarbrick, Alexander ; O’Toole, Sandra ; Timpson, Paul ; Cox, Thomas R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-08, Vol.13 (1), p.4587-4587, Article 4587
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Constitutively bound CTCF sites maintain 3D chromatin architecture and long-range epigenetically regulated domains
Author / Creator:Khoury, Amanda ; Achinger-Kawecka, Joanna ; Bert, Saul A. ; Smith, Grady C. ; French, Hugh J. ; Luu, Phuc-Loi ; Peters, Timothy J. ; Du, Qian ; Parry, Aled J. ; Valdes-Mora, Fatima ; Taberlay, Phillippa C. ; Stirzaker, Clare ; Statham, Aaron L. ; Clark, Susan J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-01, Vol.11 (1), p.54-54, Article 54
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Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer
Author / Creator:Achinger-Kawecka, Joanna ; Valdes-Mora, Fatima ; Luu, Phuc-Loi ; Giles, Katherine A. ; Caldon, C. Elizabeth ; Qu, Wenjia ; Nair, Shalima ; Soto, Sebastian ; Locke, Warwick J. ; Yeo-Teh, Nicole S. ; Gould, Cathryn M. ; Du, Qian ; Smith, Grady C. ; Ramos, Irene R. ; Fernandez, Kristine F. ; Hoon, Dave S. ; Gee, Julia M. W. ; Stirzaker, Clare ; Clark, Susan J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-01, Vol.11 (1), p.320-17, Article 320
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Histone H3-wild type diffuse midline gliomas with H3K27me3 loss are a distinct entity with exclusive EGFR or ACVR1 mutation and differential methylation of homeobox genes
Author / Creator:Ajuyah, Pamela ; Mayoh, Chelsea ; Lau, Loretta M. S. ; Barahona, Paulette ; Wong, Marie ; Chambers, Hazel ; Valdes-Mora, Fatima ; Senapati, Akanksha ; Gifford, Andrew J. ; D’Arcy, Colleen ; Hansford, Jordan R. ; Manoharan, Neevika ; Nicholls, Wayne ; Williams, Molly M. ; Wood, Paul J. ; Cowley, Mark J. ; Tyrrell, Vanessa ; Haber, Michelle ; Ekert, Paul G. ; Ziegler, David S. ; Khuong-Quang, Dong-Anh
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-03, Vol.13 (1), p.3775-3775, Article 3775
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Differential Role of Human Choline Kinase α and β Enzymes in Lipid Metabolism: Implications in Cancer Onset and Treatment
Author / Creator:Gallego-Ortega, David ; Ramirez de Molina, Ana ; Ramos, Maria Angeles ; Valdes-Mora, Fatima ; Barderas, Maria Gonzalez ; Sarmentero-Estrada, Jacinto ; Lacal, Juan Carlos
Publisher:United States: Public Library of Science
Journal title:PloS one, 2009-11, Vol.4 (11), p.e7819
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Tamoxifen-Induced Epigenetic Silencing of Oestrogen-Regulated Genes in Anti-Hormone Resistant Breast Cancer
Author / Creator:Stone, Andrew ; Valdés-Mora, Fatima ; Gee, Julia M. W. ; Farrow, Lynne ; McClelland, Richard A. ; Fiegl, Heidi ; Dutkowski, Carol ; McCloy, Rachael A. ; Sutherland, Robert L. ; Musgrove, Elizabeth A. ; Nicholson, Robert I.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-07, Vol.7 (7), p.e40466
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ALTEN: A High‐Fidelity Primary Tissue‐Engineering Platform to Assess Cellular Responses Ex Vivo
Author / Creator:Law, Andrew M. K. ; Chen, Jiamin ; Colino‐Sanguino, Yolanda ; Fuente, Laura Rodriguez de la ; Fang, Guocheng ; Grimes, Susan M. ; Lu, Hongxu ; Huang, Robert J. ; Boyle, Sarah T. ; Venhuizen, Jeron ; Castillo, Lesley ; Tavakoli, Javad ; Skhinas, Joanna N. ; Millar, Ewan K. A. ; Beretov, Julia ; Rossello, Fernando J. ; Tipper, Joanne L. ; Ormandy, Christopher J. ; Samuel, Michael S. ; Cox, Thomas R. ; Martelotto, Luciano ; Jin, Dayong ; Valdes‐Mora, Fatima ; Ji, Hanlee P. ; Gallego‐Ortega, David
Publisher:Germany: John Wiley & Sons, Inc
Journal title:Advanced science, 2022-07, Vol.9 (21), p.e2103332-n/a
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Acetylated histone variant H2A.Z is involved in the activation of neo-enhancers in prostate cancer
Author / Creator:Valdés-Mora, Fátima ; Gould, Cathryn M. ; Colino-Sanguino, Yolanda ; Qu, Wenjia ; Song, Jenny Z. ; Taylor, Kylie M. ; Buske, Fabian A. ; Statham, Aaron L. ; Nair, Shalima S. ; Armstrong, Nicola J. ; Kench, James G. ; Lee, Kenneth M. L. ; Horvath, Lisa G. ; Qiu, Minru ; Ilinykh, Alexei ; Yeo-Teh, Nicole S. ; Gallego-Ortega, David ; Stirzaker, Clare ; Clark, Susan J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-11, Vol.8 (1), p.1346-17, Article 1346
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ELF5 Suppresses Estrogen Sensitivity and Underpins the Acquisition of Antiestrogen Resistance in Luminal Breast Cancer
Author / Creator:Kalyuga, Maria ; Gallego-Ortega, David ; Lee, Heather J. ; Roden, Daniel L. ; Cowley, Mark J. ; Caldon, C. Elizabeth ; Stone, Andrew ; Allerdice, Stephanie L. ; Valdes-Mora, Fatima ; Launchbury, Rosalind ; Statham, Aaron L. ; Armstrong, Nicola ; Alles, M. Chehani ; Young, Adelaide ; Egger, Andrea ; Au, Wendy ; Piggin, Catherine L. ; Evans, Cara J. ; Ledger, Anita ; Brummer, Tilman ; Oakes, Samantha R. ; Kaplan, Warren ; Gee, Julia M. W. ; Nicholson, Robert I. ; Sutherland, Robert L. ; Swarbrick, Alexander ; Naylor, Matthew J. ; Clark, Susan J. ; Carroll, Jason S. ; Ormandy, Christopher J.
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2012-12, Vol.10 (12), p.e1001461
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H2A.Z acetylation and transcription: ready, steady, go
Author / Creator:Colino-Sanguino, Yolanda ; Clark, Susan J ; Valdes-Mora, Fatima
Publisher:England: Future Medicine Ltd
Journal title:Epigenomics, 2016-05, Vol.8 (5), p.583-586
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Stromal oncostatin M cytokine promotes breast cancer progression by reprogramming the tumor microenvironment
Author / Creator:Araujo, Angela M. ; Abaurrea, Andrea ; Azcoaga, Peio ; López-Velazco, Joanna I. ; Manzano, Sara ; Rodriguez, Javier ; Rezola, Ricardo ; Egia-Mendikute, Leire ; Valdés-Mora, Fátima ; Flores, Juana M. ; Jenkins, Liam ; Pulido, Laura ; Osorio-Querejeta, Iñaki ; Fernández-Nogueira, Patricia ; Ferrari, Nicola ; Viera, Cristina ; Martín-Martín, Natalia ; Tzankov, Alexandar ; Eppenberger-Castori, Serenella ; Alvarez-Lopez, Isabel ; Urruticoechea, Ander ; Bragado, Paloma ; Coleman, Nicholas ; Palazón, Asís ; Carracedo, Arkaitz ; Gallego-Ortega, David ; Calvo, Fernando ; Isacke, Clare M. ; Caffarel, María M. ; Lawrie, Charles H.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2022-04, Vol.132 (7), p.0_1-17
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Stromal oncostatin M cytokine promotes breast cancer progression by reprogramming the tumor microenvironment
Author / Creator:Araujo, Angela M. ; Abaurrea, Andrea ; Azcoaga, Peio ; López-Velazco, Joanna I. ; Manzano, Sara ; Rodriguez, Javier ; Rezola, Ricardo ; Egia-Mendikute, Leire ; Valdés-Mora, Fátima ; Flores, Juana M. ; Jenkins, Liam ; Pulido, Laura ; Osorio-Querejeta, Iñaki ; Fernández-Nogueira, Patricia ; Ferrari, Nicola ; Viera, Cristina ; Martín-Martín, Natalia ; Tzankov, Alexandar ; Eppenberger-Castori, Serenella ; Alvarez-Lopez, Isabel ; Urruticoechea, Ander ; Bragado, Paloma ; Coleman, Nicholas ; Palazón, Asís ; Carracedo, Arkaitz ; Gallego-Ortega, David ; Calvo, Fernando ; Isacke, Clare M. ; Caffarel, María M. ; Lawrie, Charles H.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2022-10, Vol.132 (19)
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Exploring and exploiting the aberrant DNA methylation profile of endocrine-resistant breast cancer
Author / Creator:Stone, Andrew ; Valdes-Mora, Fatima ; Clark, Susan J
Publisher:England: Future Medicine Ltd
Journal title:Epigenomics, 2013-12, Vol.5 (6), p.595-598
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ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells: e1002330
Author / Creator:Gallego-Ortega, David ; Ledger, Anita ; Roden, Daniel L ; Law, Andrew MK ; Magenau, Astrid ; Kikhtyak, Zoya ; Cho, Christina ; Allerdice, Stephanie L ; Lee, Heather J ; Valdes-Mora, Fatima ; Herrmann, David ; Salomon, Robert ; Young, Adelaide IJ ; Lee, Brian Y ; Sergio, C Marcelo ; Kaplan, Warren ; Piggin, Catherine ; Conway, James RW ; Rabinovich, Brian ; Millar, Ewan KA ; Oakes, Samantha R ; Chtanova, Tatyana ; Swarbrick, Alexander ; Naylor, Matthew J ; O'Toole, Sandra ; Green, Andrew R ; Timpson, Paul ; Gee, Julia MW ; Ellis, Ian O ; Clark, Susan J ; Ormandy, Christopher J
Publisher:San Francisco: Public Library of Science
Journal title:PLoS biology, 2015-12, Vol.13 (12)
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Differential Role of Human Choline Kinase [alpha] and [beta] Enzymes in Lipid Metabolism: Implications in Cancer Onset and Treatment
Author / Creator:Gallego-Ortega, David ; Ramirez de Molina, Ana ; Ramos, Maria Angeles ; Valdes-Mora, Fatima ; Barderas, Maria Gonzalez ; Sarmentero-Estrada, Jacinto ; Lacal, Juan Carlos
Publisher:Public Library of Science
Journal title:PloS one, 2009-11, Vol.4 (11), p.e7819
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TWIST1 Overexpression is Associated with Nodal Invasion and Male Sex in Primary Colorectal Cancer
Author / Creator:Valdés-Mora, Fátima ; Gómez del Pulgar, Teresa ; Bandrés, Eva ; Cejas, Paloma ; Ramírez de Molina, Ana ; Pérez-Palacios, Rosa ; Gallego-Ortega, David ; García-Cabezas, Miguel Angel ; Casado, Enrique ; Larrauri, Javier ; Nistal, Manuel ; González-Barón, Manuel ; García-Foncillas, Jesús ; Lacal, Juan Carlos
Publisher:New York: Springer New York
Journal title:Annals of surgical oncology, 2009-01, Vol.16 (1), p.78-87
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Differential Role of Human Choline Kinase I- and I2 Enzymes in Lipid Metabolism: Implications in Cancer Onset and Treatment
Author / Creator:Gallego-Ortega, David ; Ramirez de Molina, Ana ; Ramos, Maria Angeles ; Valdes-Mora, Fatima ; Barderas, Maria Gonzalez ; Sarmentero-Estrada, Jacinto ; Lacal, Juan Carlos ; Rutherford, Suzannah
Journal title:PloS one, 2009-01, Vol.4 (11), p.e7819-e7819
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Single-cell RNAseq uncovers involution mimicry as an aberrant development pathway during breast cancer metastasis
Author / Creator:Valdes-Mora, Fatima ; Salomon, Robert ; Gloss, Brian S ; Law, Andrew Mk ; Murphy, Kendelle ; Roden, Daniel L ; Castillo, Lesley ; Colino-Sanguino, Yolanda ; Kikhtyak, Zoya ; Farbehi, Nona ; Conway, James Rw ; Oakes, Samantha R ; Cox, Thomas ; Timpson, Paul ; Ormandy, Christopher J ; Gallego-Ortega, David
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2019-05
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Stromal oncostatin M cytokine promotes breast cancer progression by reprogramming the tumor microenvironment Stromal oncostatin M cytokine promotes breast cancer progression by reprogramming the tumor...
Author / Creator:Angela M. Araujo ; Andrea Abaurrea ; Peio Azcoaga ; Joanna I. López-Velazco ; Sara Manzano ; Javier Rodriguez ; Ricardo Rezola ; Leire Egia-Mendikute ; Fátima Valdés-Mora ; Juana M. Flores ; Liam Jenkins ; Laura Pulido ; Iñaki Osorio-Querejeta ; Patricia Fernández-Nogueira ; Nicola Ferrari ; Cristina Viera ; Natalia Martín-Martín ; Alexandar Tzankov ; Serenella Eppenberger-Castori ; Isabel Alvarez-Lopez ; Ander Urruticoechea ; Paloma Bragado ; Nicholas Coleman ; Asís Palazón ; Arkaitz Carracedo ; David Gallego-Ortega ; Fernando Calvo ; Clare M. Isacke ; María M. Caffarel ; Charles H. Lawrie
Publisher:American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2022-09, Vol.132 (19)
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Myeloid-Derived Suppressor Cells as a Therapeutic Target for Cancer

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Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis

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Constitutively bound CTCF sites maintain 3D chromatin architecture and long-range epigenetically regulated domains

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Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer

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Histone H3-wild type diffuse midline gliomas with H3K27me3 loss are a distinct entity with exclusive EGFR or ACVR1 mutation and differential methylation of homeobox genes

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Differential Role of Human Choline Kinase α and β Enzymes in Lipid Metabolism: Implications in Cancer Onset and Treatment

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Tamoxifen-Induced Epigenetic Silencing of Oestrogen-Regulated Genes in Anti-Hormone Resistant Breast Cancer

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ALTEN: A High‐Fidelity Primary Tissue‐Engineering Platform to Assess Cellular Responses Ex Vivo

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Acetylated histone variant H2A.Z is involved in the activation of neo-enhancers in prostate cancer

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ELF5 Suppresses Estrogen Sensitivity and Underpins the Acquisition of Antiestrogen Resistance in Luminal Breast Cancer

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H2A.Z acetylation and transcription: ready, steady, go

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Stromal oncostatin M cytokine promotes breast cancer progression by reprogramming the tumor microenvironment

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Stromal oncostatin M cytokine promotes breast cancer progression by reprogramming the tumor microenvironment

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Exploring and exploiting the aberrant DNA methylation profile of endocrine-resistant breast cancer

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ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells: e1002330

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Differential Role of Human Choline Kinase [alpha] and [beta] Enzymes in Lipid Metabolism: Implications in Cancer Onset and Treatment

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TWIST1 Overexpression is Associated with Nodal Invasion and Male Sex in Primary Colorectal Cancer

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Differential Role of Human Choline Kinase I- and I2 Enzymes in Lipid Metabolism: Implications in Cancer Onset and Treatment

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Single-cell RNAseq uncovers involution mimicry as an aberrant development pathway during breast cancer metastasis

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Stromal oncostatin M cytokine promotes breast cancer progression by reprogramming the tumor microenvironment Stromal oncostatin M cytokine promotes breast cancer progression by reprogramming the tumor...

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