Olanzapine-induced hyperphagia and weight gain associate with orexigenic hypothalamic neuropeptide s...
Olanzapine-induced hyperphagia and weight gain associate with orexigenic hypothalamic neuropeptide signaling without concomitant AMPK phosphorylation
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The success of antipsychotic drug treatment in patients with schizophrenia is limited by the propensity of these drugs to induce hyperphagia, weight gain and other metabolic disturbances, particularly evident for olanzapine and clozapine. However, the molecular mechanisms involved in antipsychotic-induced hyperphagia remain unclear. Here, we invest...
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Full title
Olanzapine-induced hyperphagia and weight gain associate with orexigenic hypothalamic neuropeptide signaling without concomitant AMPK phosphorylation
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TN_cdi_plos_journals_1304772517
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1304772517
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0020571
