Knock-Down of Cathepsin D Affects the Retinal Pigment Epithelium, Impairs Swim-Bladder Ontogenesis a...
Knock-Down of Cathepsin D Affects the Retinal Pigment Epithelium, Impairs Swim-Bladder Ontogenesis and Causes Premature Death in Zebrafish
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The lysosomal aspartic protease Cathepsin D (CD) is ubiquitously expressed in eukaryotic organisms. CD activity is essential to accomplish the acid-dependent extensive or partial proteolysis of protein substrates within endosomal and lysosomal compartments therein delivered via endocytosis, phagocytosis or autophagocytosis. CD may also act at physi...
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Full title
Knock-Down of Cathepsin D Affects the Retinal Pigment Epithelium, Impairs Swim-Bladder Ontogenesis and Causes Premature Death in Zebrafish
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TN_cdi_plos_journals_1304995733
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1304995733
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0021908
