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An Evolutionary Conserved Role for Anaplastic Lymphoma Kinase in Behavioral Responses to Ethanol

An Evolutionary Conserved Role for Anaplastic Lymphoma Kinase in Behavioral Responses to Ethanol

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1306248238

An Evolutionary Conserved Role for Anaplastic Lymphoma Kinase in Behavioral Responses to Ethanol

About this item

Full title

An Evolutionary Conserved Role for Anaplastic Lymphoma Kinase in Behavioral Responses to Ethanol

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011-07, Vol.6 (7), p.e22636

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Anaplastic lymphoma kinase (Alk) is a gene expressed in the nervous system that encodes a receptor tyrosine kinase commonly known for its oncogenic function in various human cancers. We have determined that Alk is associated with altered behavioral responses to ethanol in the fruit fly Drosophila melanogaster, in mice, and in humans. Mutant flies c...

Alternative Titles

Full title

An Evolutionary Conserved Role for Anaplastic Lymphoma Kinase in Behavioral Responses to Ethanol

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1306248238

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1306248238

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0022636

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