Autophagy Impairment Induces Premature Senescence in Primary Human Fibroblasts
Autophagy Impairment Induces Premature Senescence in Primary Human Fibroblasts
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Recent studies have demonstrated that activation of autophagy increases the lifespan of organisms from yeast to flies. In contrast to the lifespan extension effect in lower organisms, it has been reported that overexpression of unc-51-like kinase 3 (ULK3), the mammalian homolog of autophagy-specific gene 1 (ATG1), induces premature senescence in hu...
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Autophagy Impairment Induces Premature Senescence in Primary Human Fibroblasts
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TN_cdi_plos_journals_1306887494
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1306887494
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0023367
