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Design considerations for massively parallel sequencing studies of complex human disease

Design considerations for massively parallel sequencing studies of complex human disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1306890062

Design considerations for massively parallel sequencing studies of complex human disease

About this item

Full title

Design considerations for massively parallel sequencing studies of complex human disease

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011-08, Vol.6 (8), p.e23221

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Massively Parallel Sequencing (MPS) allows sequencing of entire exomes and genomes to now be done at reasonable cost, and its utility for identifying genes responsible for rare Mendelian disorders has been demonstrated. However, for a complex disease, study designs need to accommodate substantial degrees of locus, allelic, and phenotypic heterogene...

Alternative Titles

Full title

Design considerations for massively parallel sequencing studies of complex human disease

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1306890062

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1306890062

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0023221

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