Design considerations for massively parallel sequencing studies of complex human disease
Design considerations for massively parallel sequencing studies of complex human disease
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Massively Parallel Sequencing (MPS) allows sequencing of entire exomes and genomes to now be done at reasonable cost, and its utility for identifying genes responsible for rare Mendelian disorders has been demonstrated. However, for a complex disease, study designs need to accommodate substantial degrees of locus, allelic, and phenotypic heterogene...
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Design considerations for massively parallel sequencing studies of complex human disease
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TN_cdi_plos_journals_1306890062
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1306890062
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0023221
