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SB202190-induced cell type-specific vacuole formation and defective autophagy do not depend on p38 M...

SB202190-induced cell type-specific vacuole formation and defective autophagy do not depend on p38 M...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1307532105

SB202190-induced cell type-specific vacuole formation and defective autophagy do not depend on p38 MAP kinase inhibition

About this item

Full title

SB202190-induced cell type-specific vacuole formation and defective autophagy do not depend on p38 MAP kinase inhibition

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011-08, Vol.6 (8), p.e23054

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

SB202190, a widely used inhibitor of p38 MAPKα and β, was recently described to induce autophagic vacuoles and cell death in colon and ovarian cancer cells lines and, therefore, this effect was supposed to be specific for transformed cells and to open therapeutic options. Here, we demonstrate that SB202190 and the structurally related inhibitor SB2...

Alternative Titles

Full title

SB202190-induced cell type-specific vacuole formation and defective autophagy do not depend on p38 MAP kinase inhibition

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1307532105

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1307532105

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0023054

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