SB202190-induced cell type-specific vacuole formation and defective autophagy do not depend on p38 M...
SB202190-induced cell type-specific vacuole formation and defective autophagy do not depend on p38 MAP kinase inhibition
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United States: Public Library of Science
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English
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United States: Public Library of Science
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SB202190, a widely used inhibitor of p38 MAPKα and β, was recently described to induce autophagic vacuoles and cell death in colon and ovarian cancer cells lines and, therefore, this effect was supposed to be specific for transformed cells and to open therapeutic options. Here, we demonstrate that SB202190 and the structurally related inhibitor SB2...
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SB202190-induced cell type-specific vacuole formation and defective autophagy do not depend on p38 MAP kinase inhibition
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TN_cdi_plos_journals_1307532105
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1307532105
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1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0023054