Receptor-mediated endocytosis of α-galactosidase A in human podocytes in Fabry disease
Receptor-mediated endocytosis of α-galactosidase A in human podocytes in Fabry disease
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Injury to the glomerular podocyte is a key mechanism in human glomerular disease and podocyte repair is an important therapeutic target. In Fabry disease, podocyte injury is caused by the intracellular accumulation of globotriaosylceramide. This study identifies in the human podocyte three endocytic receptors, mannose 6-phosphate/insulin-like growt...
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Full title
Receptor-mediated endocytosis of α-galactosidase A in human podocytes in Fabry disease
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TN_cdi_plos_journals_1308506368
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1308506368
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0025065
