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Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell development

Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell development

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1309103584

Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell development

About this item

Full title

Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell development

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011-10, Vol.6 (10), p.e25812-e25812

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Interferon regulatory factor (IRF) 8 and IRF4 are structurally-related, hematopoietic cell-specific transcription factors that cooperatively regulate the differentiation of dendritic cells and B cells. Whilst in myeloid cells IRF8 is known to modulate growth and differentiation, the role of IRF4 is poorly understood. In this study, we show that IRF...

Alternative Titles

Full title

Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell development

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1309103584

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1309103584

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0025812

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