Enhancement of polymeric immunoglobulin receptor transcytosis by biparatopic VHH
Enhancement of polymeric immunoglobulin receptor transcytosis by biparatopic VHH
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
The polymeric immunoglobulin receptor (pIgR) ensures the transport of dimeric immunoglobulin A (dIgA) and pentameric immunoglobulin M (pIgM) across epithelia to the mucosal layer of for example the intestines and the lungs via transcytosis. Per day the human pIgR mediates the excretion of 2 to 5 grams of dIgA into the mucosa of luminal organs. This...
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Full title
Enhancement of polymeric immunoglobulin receptor transcytosis by biparatopic VHH
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TN_cdi_plos_journals_1309451715
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1309451715
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0026299