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Enhancement of polymeric immunoglobulin receptor transcytosis by biparatopic VHH

Enhancement of polymeric immunoglobulin receptor transcytosis by biparatopic VHH

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1309451715

Enhancement of polymeric immunoglobulin receptor transcytosis by biparatopic VHH

About this item

Full title

Enhancement of polymeric immunoglobulin receptor transcytosis by biparatopic VHH

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011-10, Vol.6 (10), p.e26299-e26299

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The polymeric immunoglobulin receptor (pIgR) ensures the transport of dimeric immunoglobulin A (dIgA) and pentameric immunoglobulin M (pIgM) across epithelia to the mucosal layer of for example the intestines and the lungs via transcytosis. Per day the human pIgR mediates the excretion of 2 to 5 grams of dIgA into the mucosa of luminal organs. This...

Alternative Titles

Full title

Enhancement of polymeric immunoglobulin receptor transcytosis by biparatopic VHH

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1309451715

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1309451715

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0026299

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