Modeling of human prokineticin receptors: interactions with novel small-molecule binders and potenti...
Modeling of human prokineticin receptors: interactions with novel small-molecule binders and potential off-target drugs
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
The Prokineticin receptor (PKR) 1 and 2 subtypes are novel members of family A GPCRs, which exhibit an unusually high degree of sequence similarity. Prokineticins (PKs), their cognate ligands, are small secreted proteins of ∼80 amino acids; however, non-peptidic low-molecular weight antagonists have also been identified. PKs and their receptors pla...
Alternative Titles
Full title
Modeling of human prokineticin receptors: interactions with novel small-molecule binders and potential off-target drugs
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1310157696
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1310157696
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0027990