Log in to save to my catalogue

Concentration-dependent dual effects of hydrogen peroxide on insulin signal transduction in H4IIEC h...

Concentration-dependent dual effects of hydrogen peroxide on insulin signal transduction in H4IIEC h...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312101292

Concentration-dependent dual effects of hydrogen peroxide on insulin signal transduction in H4IIEC hepatocytes

About this item

Full title

Concentration-dependent dual effects of hydrogen peroxide on insulin signal transduction in H4IIEC hepatocytes

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011-11, Vol.6 (11), p.e27401

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Oxidative stress induced by the accumulation of reactive oxygen species (ROS) has a causal role in the development of insulin resistance, whereas ROS themselves function as intracellular second messengers that promote insulin signal transduction. ROS can act both positively and negatively on insulin signaling, but the molecular mechanisms controlli...

Alternative Titles

Full title

Concentration-dependent dual effects of hydrogen peroxide on insulin signal transduction in H4IIEC hepatocytes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1312101292

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312101292

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0027401

How to access this item