Concentration-dependent dual effects of hydrogen peroxide on insulin signal transduction in H4IIEC h...
Concentration-dependent dual effects of hydrogen peroxide on insulin signal transduction in H4IIEC hepatocytes
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Oxidative stress induced by the accumulation of reactive oxygen species (ROS) has a causal role in the development of insulin resistance, whereas ROS themselves function as intracellular second messengers that promote insulin signal transduction. ROS can act both positively and negatively on insulin signaling, but the molecular mechanisms controlli...
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Full title
Concentration-dependent dual effects of hydrogen peroxide on insulin signal transduction in H4IIEC hepatocytes
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TN_cdi_plos_journals_1312101292
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312101292
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0027401