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101 results for Takamura,+Toshinari

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LECT2 as a hepatokine links liver steatosis to inflammation via activating tissue macrophages in NASH
Author / Creator:Takata, Noboru ; Ishii, Kiyo-aki ; Takayama, Hiroaki ; Nagashimada, Mayumi ; Kamoshita, Kyoko ; Tanaka, Takeo ; Kikuchi, Akihiro ; Takeshita, Yumie ; Matsumoto, Yukako ; Ota, Tsuguhito ; Yamamoto, Yasuhiko ; Yamagoe, Satoshi ; Seki, Akihiro ; Sakai, Yoshio ; Kaneko, Shuichi ; Takamura, Toshinari
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-01, Vol.11 (1), p.555-555, Article 555
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Selenoprotein P-neutralizing antibodies improve insulin secretion and glucose sensitivity in type 2 diabetes mouse models
Author / Creator:Mita, Yuichiro ; Nakayama, Kaho ; Inari, Shogo ; Nishito, Yukina ; Yoshioka, Yuya ; Sakai, Naoko ; Sotani, Kanade ; Nagamura, Takahiro ; Kuzuhara, Yuki ; Inagaki, Kumi ; Iwasaki, Miki ; Misu, Hirofumi ; Ikegawa, Masaya ; Takamura, Toshinari ; Noguchi, Noriko ; Saito, Yoshiro
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-11, Vol.8 (1), p.1658-17, Article 1658
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Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers
Author / Creator:Kawaguchi, Takahisa ; Shima, Toshihide ; Mizuno, Masayuki ; Mitsumoto, Yasuhide ; Umemura, Atsushi ; Kanbara, Yoshihiro ; Tanaka, Saiyu ; Sumida, Yoshio ; Yasui, Kohichiro ; Takahashi, Meiko ; Matsuo, Keitaro ; Itoh, Yoshito ; Tokushige, Katsutoshi ; Hashimoto, Etsuko ; Kiyosawa, Kendo ; Kawaguchi, Masanori ; Itoh, Hiroyuki ; Uto, Hirofumi ; Komorizono, Yasuji ; Shirabe, Ken ; Takami, Shiro ; Takamura, Toshinari ; Kawanaka, Miwa ; Yamada, Ryo ; Matsuda, Fumihiko ; Okanoue, Takeshi
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-01, Vol.13 (1), p.e0185490-e0185490
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CCR5 Plays a Critical Role in Obesity-Induced Adipose Tissue Inflammation and Insulin Resistance by Regulating Both Macrophage Recruitment and M1/M2 Status
Author / Creator:Kitade, Hironori ; Sawamoto, Kazuki ; Nagashimada, Mayumi ; Inoue, Hiroshi ; Yamamoto, Yasuhiko ; Sai, Yoshimichi ; Takamura, Toshinari ; Yamamoto, Hiroshi ; Miyamoto, Ken-ichi ; Ginsberg, Henry N. ; Mukaida, Naofumi ; Kaneko, Shuichi ; Ota, Tsuguhito
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2012-07, Vol.61 (7), p.1680-1690
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Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle
Author / Creator:Misu, Hirofumi ; Takayama, Hiroaki ; Saito, Yoshiro ; Mita, Yuichiro ; Kikuchi, Akihiro ; Ishii, Kiyo-aki ; Chikamoto, Keita ; Kanamori, Takehiro ; Tajima, Natsumi ; Lan, Fei ; Takeshita, Yumie ; Honda, Masao ; Tanaka, Mutsumi ; Kato, Seiji ; Matsuyama, Naoto ; Yoshioka, Yuya ; Iwayama, Kaito ; Tokuyama, Kumpei ; Akazawa, Nobuhiko ; Maeda, Seiji ; Takekoshi, Kazuhiro ; Matsugo, Seiichi ; Noguchi, Noriko ; Kaneko, Shuichi ; Takamura, Toshinari
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2017-04, Vol.23 (4), p.508-516
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Genetic Polymorphisms of the Human PNPLA3 Gene Are Strongly Associated with Severity of Non-Alcoholic Fatty Liver Disease in Japanese
Author / Creator:Kawaguchi, Takahisa ; Sumida, Yoshio ; Umemura, Atsushi ; Matsuo, Keitaro ; Takahashi, Meiko ; Takamura, Toshinari ; Yasui, Kohichiroh ; Saibara, Toshiji ; Hashimoto, Etsuko ; Kawanaka, Miwa ; Watanabe, Sumio ; Kawata, Sumio ; Imai, Yasuharu ; Kokubo, Miki ; Shima, Toshihide ; Park, Hyohun ; Tanaka, Hideo ; Tajima, Kazuo ; Yamada, Ryo ; Matsuda, Fumihiko
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-06, Vol.7 (6), p.e38322-e38322
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Eight-year longitudinal study of whole blood gene expression profiles in individuals undergoing long-term medical follow-up
Author / Creator:Sakai, Yoshio ; Nasti, Alessandro ; Takeshita, Yumie ; Okumura, Miki ; Kitajima, Shinji ; Honda, Masao ; Wada, Takashi ; Nakamura, Seiji ; Takamura, Toshinari ; Tamura, Takuro ; Matsubara, Kenichi ; Kaneko, Shuichi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-08, Vol.11 (1), p.16564-16564, Article 16564
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ArticlesPeer ReviewedFull Text
LECT2 Deletion Exacerbates Liver Steatosis and Macrophage Infiltration in a Male Mouse Model of LPS-mediated NASH
Author / Creator:Tanida, Ryota ; Goto, Hisanori ; Takayama, Hiroaki ; Nakano, Yujiro ; Oo, Hein Ko ; Galicia-Medina, Cynthia Monserrat ; Takahashi, Kenta ; Ishii, Kiyo-Aki ; Goli, Arman Syah ; Matsuzaka, Takashi ; Harada, Kenichi ; Takamura, Toshinari
Publisher:US: The Endocrine Society
Journal title:Endocrinology, 2024-05, Vol.165 (7), p.1
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ArticlesPeer ReviewedFull Text
Concentration-dependent Dual Effects of Hydrogen Peroxide on Insulin Signal Transduction in H4IIEC Hepatocytes
Author / Creator:Iwakami, Satoshi ; Misu, Hirofumi ; Takeda, Takashi ; Sugimori, Makoto ; Matsugo, Seiichi ; Kaneko, Shuichi ; Takamura, Toshinari
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-11, Vol.6 (11), p.e27401
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Hepatocellular carcinoma as a leading cause of cancer-related deaths in Japanese type 2 diabetes mellitus patients
Author / Creator:Shima, Toshihide ; Uto, Hirofumi ; Ueki, Kohjiro ; Kohgo, Yutaka ; Yasui, Kohichiroh ; Nakamura, Naoto ; Nakatou, Tatsuaki ; Takamura, Toshinari ; Kawata, Sumio ; Notsumata, Kazuo ; Sakai, Kyoko ; Tateishi, Ryosuke ; Okanoue, Takeshi
Publisher:Tokyo: Springer Japan
Journal title:Journal of gastroenterology, 2019-01, Vol.54 (1), p.64-77
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Inhibin βE (INHBE) is a possible insulin resistance-associated hepatokine identified by comprehensive gene expression analysis in human liver biopsy samples
Author / Creator:Sugiyama, Masakazu ; Kikuchi, Akihiro ; Misu, Hirofumi ; Igawa, Hirobumi ; Ashihara, Motooki ; Kushima, Youichi ; Honda, Kiyofumi ; Suzuki, Yoshiyuki ; Kawabe, Yoshiki ; Kaneko, Shuichi ; Takamura, Toshinari
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-03, Vol.13 (3), p.e0194798-e0194798
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Long-Term Outcomes of Japanese Type 2 Diabetic Patients With Biopsy-Proven Diabetic Nephropathy
Author / Creator:Shimizu, Miho ; Furuichi, Kengo ; Toyama, Tadashi ; Kitajima, Shinji ; Hara, Akinori ; Kitagawa, Kiyoki ; Iwata, Yasunori ; Sakai, Norihiko ; Takamura, Toshinari ; Yoshimura, Mitsuhiro ; Yokoyama, Hitoshi ; Kaneko, Shuichi ; Wada, Takashi
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes care, 2013-11, Vol.36 (11), p.3655-3662
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Inverse Correlation between Serum Levels of Selenoprotein P and Adiponectin in Patients with Type 2 Diabetes
Author / Creator:Misu, Hirofumi ; Ishikura, Kazuhide ; Kurita, Seiichiro ; Takeshita, Yumie ; Ota, Tsuguhito ; Saito, Yoshiro ; Takahashi, Kazuhiko ; Kaneko, Shuichi ; Takamura, Toshinari
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-04, Vol.7 (4), p.e34952-e34952
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Serum selenoprotein P, but not selenium, predicts future hyperglycemia in a general Japanese population
Author / Creator:Oo, Swe Mar ; Misu, Hirofumi ; Saito, Yoshiro ; Tanaka, Mutsumi ; Kato, Seiji ; Kita, Yuki ; Takayama, Hiroaki ; Takeshita, Yumie ; Kanamori, Takehiro ; Nagano, Toru ; Nakagen, Masatoshi ; Urabe, Takeshi ; Matsuyama, Naoto ; Kaneko, Shuichi ; Takamura, Toshinari
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-11, Vol.8 (1), p.16727-10, Article 16727
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Reduction of estimated fluid volumes following initiation of empagliflozin in patients with type 2 diabetes and cardiovascular disease: a secondary analysis of the placebo-controlled, randomized EMBLE...
Author / Creator:Tanaka, Atsushi ; Shimabukuro, Michio ; Teragawa, Hiroki ; Okada, Yosuke ; Takamura, Toshinari ; Taguchi, Isao ; Toyoda, Shigeru ; Tomiyama, Hirofumi ; Ueda, Shinichiro ; Higashi, Yukihito ; Node, Koichi
Publisher:England: BioMed Central
Journal title:Cardiovascular diabetology, 2021-06, Vol.20 (1), p.105-105, Article 105
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Thyroid Arteriovenous Malformation in Hereditary Hemorrhagic Telangiectasia: Insights on Successful Noninvasive Imaging
Author / Creator:Goto, Hisanori ; Tanimura, Iyo ; Nakano, Yujiro ; Takeshita, Yumie ; Takamura, Toshinari
Publisher:US: The Endocrine Society
Journal title:JCEM Case Reports, 2024-08, Vol.2 (8), p.luae138
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Metformin Prevents and Reverses Inflammation in a Non-Diabetic Mouse Model of Nonalcoholic Steatohepatitis
Author / Creator:Kita, Yuki ; Takamura, Toshinari ; Misu, Hirofumi ; Ota, Tsuguhito ; Kurita, Seiichiro ; Takeshita, Yumie ; Uno, Masafumi ; Matsuzawa-Nagata, Naoto ; Kato, Ken-ichiro ; Ando, Hitoshi ; Fujimura, Akio ; Hayashi, Koji ; Kimura, Toru ; Ni, Yinhua ; Otoda, Toshiki ; Miyamoto, Ken-ichi ; Zen, Yoh ; Nakanuma, Yasuni ; Kaneko, Shuichi
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-09, Vol.7 (9), p.e43056
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Proteasome Dysfunction Mediates Obesity-Induced Endoplasmic Reticulum Stress and Insulin Resistance in the Liver
Author / Creator:Otoda, Toshiki ; Takamura, Toshinari ; Misu, Hirofumi ; Ota, Tsuguhito ; Murata, Shigeo ; Hayashi, Hiroto ; Takayama, Hiroaki ; Kikuchi, Akihiro ; Kanamori, Takehiro ; Shima, Kosuke R. ; Lan, Fei ; Takeda, Takashi ; Kurita, Seiichiro ; Ishikura, Kazuhide ; Kita, Yuki ; Iwayama, Kaito ; Kato, Ken-ichiro ; Uno, Masafumi ; Takeshita, Yumie ; Yamamoto, Miyuki ; Tokuyama, Kunpei ; Iseki, Shoichi ; Tanaka, Keiji ; Kaneko, Shuichi
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2013-03, Vol.62 (3), p.811-824
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Leukocyte cell-derived chemotaxin 2 is an antiviral regulator acting through the proto-oncogene MET
Author / Creator:Shirasaki, Takayoshi ; Yamagoe, Satoshi ; Shimakami, Tetsuro ; Murai, Kazuhisa ; Imamura, Ryu ; Ishii, Kiyo-Aki ; Takayama, Hiroaki ; Matsumoto, Yukako ; Tajima-Shirasaki, Natsumi ; Nagata, Naoto ; Shimizu, Ryogo ; Yamanaka, Souma ; Abe, Atsushi ; Omura, Hitoshi ; Kawaguchi, Kazunori ; Okada, Hikari ; Yamashita, Taro ; Yoshikawa, Tomoki ; Takimoto, Kazuhiro ; Taharaguchi, Motoko ; Takatsuka, Shogo ; Miyazaki, Yoshitsugu ; Tamai, Toshikatsu ; Tanabe, Yamato ; Kurachi, Makoto ; Yamamoto, Yasuhiko ; Kaneko, Shuichi ; Matsumoto, Kunio ; Takamura, Toshinari ; Honda, Masao
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-06, Vol.13 (1), p.3176-3176, Article 3176
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Metabolic and sympathovagal effects of bolus insulin glulisine versus basal insulin glargine therapy in people with type 2 diabetes: A randomized controlled study
Author / Creator:Takeshita, Yumie ; Tanaka, Takeo ; Wakakuri, Hitomi ; Kita, Yuki ; Kanamori, Takehiro ; Takamura, Toshinari
Publisher:Japan: John Wiley & Sons, Inc
Journal title:Journal of diabetes investigation, 2021-07, Vol.12 (7), p.1193-1201
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LECT2 as a hepatokine links liver steatosis to inflammation via activating tissue macrophages in NASH

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Selenoprotein P-neutralizing antibodies improve insulin secretion and glucose sensitivity in type 2 diabetes mouse models

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Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers

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CCR5 Plays a Critical Role in Obesity-Induced Adipose Tissue Inflammation and Insulin Resistance by Regulating Both Macrophage Recruitment and M1/M2 Status

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Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle

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Genetic Polymorphisms of the Human PNPLA3 Gene Are Strongly Associated with Severity of Non-Alcoholic Fatty Liver Disease in Japanese

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Eight-year longitudinal study of whole blood gene expression profiles in individuals undergoing long-term medical follow-up

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LECT2 Deletion Exacerbates Liver Steatosis and Macrophage Infiltration in a Male Mouse Model of LPS-mediated NASH

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Concentration-dependent Dual Effects of Hydrogen Peroxide on Insulin Signal Transduction in H4IIEC Hepatocytes

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Hepatocellular carcinoma as a leading cause of cancer-related deaths in Japanese type 2 diabetes mellitus patients

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Inhibin βE (INHBE) is a possible insulin resistance-associated hepatokine identified by comprehensive gene expression analysis in human liver biopsy samples

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Long-Term Outcomes of Japanese Type 2 Diabetic Patients With Biopsy-Proven Diabetic Nephropathy

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Inverse Correlation between Serum Levels of Selenoprotein P and Adiponectin in Patients with Type 2 Diabetes

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Serum selenoprotein P, but not selenium, predicts future hyperglycemia in a general Japanese population

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Reduction of estimated fluid volumes following initiation of empagliflozin in patients with type 2 diabetes and cardiovascular disease: a secondary analysis of the placebo-controlled, randomized EMBLE...

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Thyroid Arteriovenous Malformation in Hereditary Hemorrhagic Telangiectasia: Insights on Successful Noninvasive Imaging

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Metformin Prevents and Reverses Inflammation in a Non-Diabetic Mouse Model of Nonalcoholic Steatohepatitis

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Proteasome Dysfunction Mediates Obesity-Induced Endoplasmic Reticulum Stress and Insulin Resistance in the Liver

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Leukocyte cell-derived chemotaxin 2 is an antiviral regulator acting through the proto-oncogene MET

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Metabolic and sympathovagal effects of bolus insulin glulisine versus basal insulin glargine therapy in people with type 2 diabetes: A randomized controlled study

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