Activation of the alternative NFκB pathway improves disease symptoms in a model of Sjogren's syndrom...
Activation of the alternative NFκB pathway improves disease symptoms in a model of Sjogren's syndrome
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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The purpose of our study was to understand if Toll-like receptor 9 (TLR9) activation could contribute to the control of inflammation in Sjogren's syndrome. To this end, we manipulated TLR9 signaling in non-obese diabetic (NOD) and TLR9(-/-) mice using agonistic CpG oligonucleotide aptamers, TLR9 inhibitors, and the in-house oligonucleotide BL-7040....
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Full title
Activation of the alternative NFκB pathway improves disease symptoms in a model of Sjogren's syndrome
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TN_cdi_plos_journals_1312169541
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312169541
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0028727
