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Macrophage-specific chemokines induced via innate immunity by amino acid copolymers and their role i...

Macrophage-specific chemokines induced via innate immunity by amino acid copolymers and their role i...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312178326

Macrophage-specific chemokines induced via innate immunity by amino acid copolymers and their role in EAE

About this item

Full title

Macrophage-specific chemokines induced via innate immunity by amino acid copolymers and their role in EAE

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011-12, Vol.6 (12), p.e26274-e26274

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

The random amino acid copolymer poly(Y,E,A,K)(n) (Copaxone®) is widely used in multiple sclerosis treatment and a second generation copolymer poly(Y,F,A,K)(n) with enhanced efficacy in experimental autoimmune encephalomyelitis in mice has been described. A major mechanism through which copolymers function to ameliorate disease is the generation of...

Alternative Titles

Full title

Macrophage-specific chemokines induced via innate immunity by amino acid copolymers and their role in EAE

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1312178326

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312178326

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0026274

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