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Silencing of keratinocyte growth factor receptor restores 5-fluorouracil and tamoxifen efficacy on r...

Silencing of keratinocyte growth factor receptor restores 5-fluorouracil and tamoxifen efficacy on r...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312290901

Silencing of keratinocyte growth factor receptor restores 5-fluorouracil and tamoxifen efficacy on responsive cancer cells

About this item

Full title

Silencing of keratinocyte growth factor receptor restores 5-fluorouracil and tamoxifen efficacy on responsive cancer cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2008-06, Vol.3 (6), p.e2528-e2528

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Keratinocyte growth factor receptor (KGFR) is a splice variant of the FGFR2 gene expressed in epithelial cells. Activation of KGFR is a key factor in the regulation of physiological processes in epithelial cells such as proliferation, differentiation and wound healing. Alterations of KGFR signaling have been linked to the pathogenesis of different...

Alternative Titles

Full title

Silencing of keratinocyte growth factor receptor restores 5-fluorouracil and tamoxifen efficacy on responsive cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1312290901

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312290901

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0002528

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