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OPCML is a broad tumor suppressor for multiple carcinomas and lymphomas with frequently epigenetic i...

OPCML is a broad tumor suppressor for multiple carcinomas and lymphomas with frequently epigenetic i...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312295605

OPCML is a broad tumor suppressor for multiple carcinomas and lymphomas with frequently epigenetic inactivation

About this item

Full title

OPCML is a broad tumor suppressor for multiple carcinomas and lymphomas with frequently epigenetic inactivation

Publisher

United States: Public Library of Science

Journal title

PloS one, 2008-08, Vol.3 (8), p.e2990-e2990

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Identification of tumor suppressor genes (TSGs) silenced by CpG methylation uncovers the molecular mechanism of tumorigenesis and potential tumor biomarkers. Loss of heterozygosity at 11q25 is common in multiple tumors including nasopharyngeal carcinoma (NPC). OPCML, located at 11q25, is one of the downregulated genes we identified through digital...

Alternative Titles

Full title

OPCML is a broad tumor suppressor for multiple carcinomas and lymphomas with frequently epigenetic inactivation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1312295605

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312295605

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0002990

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