HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein respon...
HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Neurologic disease caused by human immunodeficiency virus type 1 (HIV-1) is ultimately refractory to highly active antiretroviral therapy (HAART) because of failure of complete virus eradication in the central nervous system (CNS), and disruption of normal neural signaling events by virally induced chronic neuroinflammation. We have previously repo...
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Full title
HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization
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TN_cdi_plos_journals_1312311924
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312311924
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0003731
