Identification of a regulatory T cell specific cell surface molecule that mediates suppressive signa...
Identification of a regulatory T cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 expression
About this item
Full title
Author / Creator
Wang, Rui , Wan, Qi , Kozhaya, Lina , Fujii, Hodaka and Unutmaz, Derya
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Regulatory T (T(reg)) cells control immune activation and maintain tolerance. How T(regs) mediate their suppressive function is unclear. Here we identified a cell surface molecule, called GARP, (or LRRC32), which within T cells is specifically expressed in T(regs) activated through the T cell receptor (TCR). Ectopic expression of GARP in human naïv...
Alternative Titles
Full title
Identification of a regulatory T cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 expression
Authors, Artists and Contributors
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Record Identifier
TN_cdi_plos_journals_1312318317
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312318317
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0002705
