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The POM Monoclonals: A Comprehensive Set of Antibodies to Non-Overlapping Prion Protein Epitopes

The POM Monoclonals: A Comprehensive Set of Antibodies to Non-Overlapping Prion Protein Epitopes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312319374

The POM Monoclonals: A Comprehensive Set of Antibodies to Non-Overlapping Prion Protein Epitopes

About this item

Full title

The POM Monoclonals: A Comprehensive Set of Antibodies to Non-Overlapping Prion Protein Epitopes

Publisher

United States: Public Library of Science

Journal title

PloS one, 2008-12, Vol.3 (12), p.e3872-e3872

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

PrP(Sc), a misfolded and aggregated form of the cellular prion protein PrP(C), is the only defined constituent of the transmissible agent causing prion diseases. Expression of PrP(C) in the host organism is necessary for prion replication and for prion neurotoxicity. Understanding prion diseases necessitates detailed structural insights into PrP(C)...

Alternative Titles

Full title

The POM Monoclonals: A Comprehensive Set of Antibodies to Non-Overlapping Prion Protein Epitopes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1312319374

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312319374

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0003872

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