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Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia

Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312320853

Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia

About this item

Full title

Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia

Publisher

United States: Public Library of Science

Journal title

PloS one, 2008-10, Vol.3 (10), p.e3581-e3581

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The Birt-Hogg-Dubé (BHD) disease is a genetic cancer syndrome. The responsible gene, BHD, has been identified by positional cloning and thought to be a novel tumor suppressor gene. BHD mutations cause many types of diseases including renal cell carcinomas, fibrofolliculomas, spontaneous pneumothorax, lung cysts, and colonic polyps/cancers. By combi...

Alternative Titles

Full title

Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1312320853

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312320853

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0003581

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