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Myocardial hypertrophy overrides the angiogenic response to hypoxia

Myocardial hypertrophy overrides the angiogenic response to hypoxia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312323198

Myocardial hypertrophy overrides the angiogenic response to hypoxia

About this item

Full title

Myocardial hypertrophy overrides the angiogenic response to hypoxia

Publisher

United States: Public Library of Science

Journal title

PloS one, 2008-12, Vol.3 (12), p.e4042-e4042

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Cyanosis and myocardial hypertrophy frequently occur in combination. Hypoxia or cyanosis can be potent inducers of angiogenesis, regulating the expression of hypoxia-inducible factors (HIF), vascular endothelial growth factors (VEGF), and VEGF receptors (VEGFR-1 and 2); in contrast, pressure overload hypertrophy is often associated with impaired pr...

Alternative Titles

Full title

Myocardial hypertrophy overrides the angiogenic response to hypoxia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1312323198

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312323198

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0004042

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