Modeling an Evolutionary Conserved Circadian Cis-Element
Modeling an Evolutionary Conserved Circadian Cis-Element
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Contents
Circadian oscillator networks rely on a transcriptional activator called CLOCK/CYCLE (CLK/CYC) in insects and CLOCK/BMAL1 or NPAS2/BMAL1 in mammals. Identifying the targets of this heterodimeric basic-helix-loop-helix (bHLH) transcription factor poses challenges and it has been difficult to decipher its specific sequence affinity beyond a canonical...
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Full title
Modeling an Evolutionary Conserved Circadian Cis-Element
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TN_cdi_plos_journals_1312438451
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312438451
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ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.0040038
