Modeling evolutionary dynamics of epigenetic mutations in hierarchically organized tumors
Modeling evolutionary dynamics of epigenetic mutations in hierarchically organized tumors
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The cancer stem cell (CSC) concept is a highly debated topic in cancer research. While experimental evidence in favor of the cancer stem cell theory is apparently abundant, the results are often criticized as being difficult to interpret. An important reason for this is that most experimental data that support this model rely on transplantation stu...
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Modeling evolutionary dynamics of epigenetic mutations in hierarchically organized tumors
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TN_cdi_plos_journals_1313185569
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313185569
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ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1001132