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Modeling evolutionary dynamics of epigenetic mutations in hierarchically organized tumors

Modeling evolutionary dynamics of epigenetic mutations in hierarchically organized tumors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313185569

Modeling evolutionary dynamics of epigenetic mutations in hierarchically organized tumors

About this item

Full title

Modeling evolutionary dynamics of epigenetic mutations in hierarchically organized tumors

Publisher

United States: Public Library of Science

Journal title

PLoS computational biology, 2011-05, Vol.7 (5), p.e1001132-e1001132

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The cancer stem cell (CSC) concept is a highly debated topic in cancer research. While experimental evidence in favor of the cancer stem cell theory is apparently abundant, the results are often criticized as being difficult to interpret. An important reason for this is that most experimental data that support this model rely on transplantation stu...

Alternative Titles

Full title

Modeling evolutionary dynamics of epigenetic mutations in hierarchically organized tumors

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1313185569

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313185569

Other Identifiers

ISSN

1553-7358,1553-734X

E-ISSN

1553-7358

DOI

10.1371/journal.pcbi.1001132

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