Accelerated Profile HMM Searches
Accelerated Profile HMM Searches
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Profile hidden Markov models (profile HMMs) and probabilistic inference methods have made important contributions to the theory of sequence database homology search. However, practical use of profile HMM methods has been hindered by the computational expense of existing software implementations. Here I describe an acceleration heuristic for profile...
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Full title
Accelerated Profile HMM Searches
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TN_cdi_plos_journals_1313186425
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313186425
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ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1002195