Retrotransposon Silencing by DNA Methylation Can Drive Mammalian Genomic Imprinting
Retrotransposon Silencing by DNA Methylation Can Drive Mammalian Genomic Imprinting
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Among mammals, only eutherians and marsupials are viviparous and have genomic imprinting that leads to parent-of-origin-specific differential gene expression. We used comparative analysis to investigate the origin of genomic imprinting in mammals. PEG10 (paternally expressed 10) is a retrotransposon-derived imprinted gene that has an essential role...
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Retrotransposon Silencing by DNA Methylation Can Drive Mammalian Genomic Imprinting
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TN_cdi_plos_journals_1313482922
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313482922
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.0030055
