dAtaxin-2 Mediates Expanded Ataxin-1-Induced Neurodegeneration in a Drosophila Model of SCA1
dAtaxin-2 Mediates Expanded Ataxin-1-Induced Neurodegeneration in a Drosophila Model of SCA1
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Spinocerebellar ataxias (SCAs) are a genetically heterogeneous group of neurodegenerative disorders sharing atrophy of the cerebellum as a common feature. SCA1 and SCA2 are two ataxias caused by expansion of polyglutamine tracts in Ataxin-1 (ATXN1) and Ataxin-2 (ATXN2), respectively, two proteins that are otherwise unrelated. Here, we use a Drosoph...
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dAtaxin-2 Mediates Expanded Ataxin-1-Induced Neurodegeneration in a Drosophila Model of SCA1
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TN_cdi_plos_journals_1313483038
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313483038
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1553-7404,1553-7390
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1553-7404
DOI
10.1371/journal.pgen.0030234
