Common genetic variants near the Brittle Cornea Syndrome locus ZNF469 influence the blinding disease...
Common genetic variants near the Brittle Cornea Syndrome locus ZNF469 influence the blinding disease risk factor central corneal thickness
About this item
Full title
Author / Creator
Lu, Yi , Dimasi, David P , Hysi, Pirro G , Hewitt, Alex W , Burdon, Kathryn P , Toh, Tze'Yo , Ruddle, Jonathan B , Li, Yi Ju , Mitchell, Paul , Healey, Paul R , Montgomery, Grant W , Hansell, Narelle , Spector, Timothy D , Martin, Nicholas G , Young, Terri L , Hammond, Christopher J , Macgregor, Stuart , Craig, Jamie E and Mackey, David A
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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More information
Scope and Contents
Contents
Central corneal thickness (CCT), one of the most highly heritable human traits (h(2) typically>0.9), is important for the diagnosis of glaucoma and a potential risk factor for glaucoma susceptibility. We conducted genome-wide association studies in five cohorts from Australia and the United Kingdom (total N = 5058). Three cohorts were based on indi...
Alternative Titles
Full title
Common genetic variants near the Brittle Cornea Syndrome locus ZNF469 influence the blinding disease risk factor central corneal thickness
Authors, Artists and Contributors
Author / Creator
Dimasi, David P
Hysi, Pirro G
Hewitt, Alex W
Burdon, Kathryn P
Toh, Tze'Yo
Ruddle, Jonathan B
Li, Yi Ju
Mitchell, Paul
Healey, Paul R
Montgomery, Grant W
Hansell, Narelle
Spector, Timothy D
Martin, Nicholas G
Young, Terri L
Hammond, Christopher J
Macgregor, Stuart
Craig, Jamie E
Mackey, David A
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1313509525
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313509525
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1000947
