Genetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tube...
Genetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tuberculosis
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Author / Creator
Davila, Sonia , Hibberd, Martin L , Hari Dass, Ranjeeta , Wong, Hazel E E , Sahiratmadja, Edhyana , Bonnard, Carine , Alisjahbana, Bachti , Szeszko, Jeffrey S , Balabanova, Yanina , Drobniewski, Francis , van Crevel, Reinout , van de Vosse, Esther , Nejentsev, Sergey , Ottenhoff, Tom H M and Seielstad, Mark
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Despite high rates of exposure, only 5-10% of people infected with Mycobacterium tuberculosis will develop active tuberculosis (TB) disease, suggesting a significant role for genetic variation in the human immune response to this infection. Here, we studied TB association and expression of 18 genes involved in the Toll-like receptor (TLR) pathways....
Alternative Titles
Full title
Genetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tuberculosis
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Record Identifier
TN_cdi_plos_journals_1313514637
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313514637
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1000218
