Decreased mitochondrial DNA mutagenesis in human colorectal cancer
Decreased mitochondrial DNA mutagenesis in human colorectal cancer
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Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Genome instability is regarded as a hallmark of cancer. Human tumors frequently carry clonally expanded mutations in their mitochondrial DNA (mtDNA), some of which may drive cancer progression and metastasis. The high prevalence of clonal mutations in tumor mtDNA has commonly led to the assumption that the mitochondrial genome in cancer is genetica...
Alternative Titles
Full title
Decreased mitochondrial DNA mutagenesis in human colorectal cancer
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TN_cdi_plos_journals_1313515534
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313515534
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1002689
