Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that...
Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability
About this item
Full title
Author / Creator
Sanna, Serena , Li, Bingshan , Mulas, Antonella , Sidore, Carlo , Kang, Hyun M , Jackson, Anne U , Piras, Maria Grazia , Usala, Gianluca , Maninchedda, Giuseppe , Sassu, Alessandro , Serra, Fabrizio , Palmas, Maria Antonietta , Wood, 3rd, William H , Njølstad, Inger , Laakso, Markku , Hveem, Kristian , Tuomilehto, Jaakko , Lakka, Timo A , Rauramaa, Rainer , Boehnke, Michael , Cucca, Francesco , Uda, Manuela , Schlessinger, David , Nagaraja, Ramaiah and Abecasis, Gonçalo R
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
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More information
Scope and Contents
Contents
Complex trait genome-wide association studies (GWAS) provide an efficient strategy for evaluating large numbers of common variants in large numbers of individuals and for identifying trait-associated variants. Nevertheless, GWAS often leave much of the trait heritability unexplained. We hypothesized that some of this unexplained heritability might...
Alternative Titles
Full title
Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability
Authors, Artists and Contributors
Author / Creator
Li, Bingshan
Mulas, Antonella
Sidore, Carlo
Kang, Hyun M
Jackson, Anne U
Piras, Maria Grazia
Usala, Gianluca
Maninchedda, Giuseppe
Sassu, Alessandro
Serra, Fabrizio
Palmas, Maria Antonietta
Wood, 3rd, William H
Njølstad, Inger
Laakso, Markku
Hveem, Kristian
Tuomilehto, Jaakko
Lakka, Timo A
Rauramaa, Rainer
Boehnke, Michael
Cucca, Francesco
Uda, Manuela
Schlessinger, David
Nagaraja, Ramaiah
Abecasis, Gonçalo R
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1313529630
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313529630
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1002198
