Log in to save to my catalogue

Base Damage within Single-Strand DNA Underlies In Vivo Hypermutability Induced by a Ubiquitous Envir...

Base Damage within Single-Strand DNA Underlies In Vivo Hypermutability Induced by a Ubiquitous Envir...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313535851

Base Damage within Single-Strand DNA Underlies In Vivo Hypermutability Induced by a Ubiquitous Environmental Agent

About this item

Full title

Base Damage within Single-Strand DNA Underlies In Vivo Hypermutability Induced by a Ubiquitous Environmental Agent

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2012-12, Vol.8 (12), p.e1003149

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Chromosomal DNA must be in single-strand form for important transactions such as replication, transcription, and recombination to occur. The single-strand DNA (ssDNA) is more prone to damage than double-strand DNA (dsDNA), due to greater exposure of chemically reactive moieties in the nitrogenous bases. Thus, there can be agents that damage regions...

Alternative Titles

Full title

Base Damage within Single-Strand DNA Underlies In Vivo Hypermutability Induced by a Ubiquitous Environmental Agent

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1313535851

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313535851

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1003149

How to access this item