Base Damage within Single-Strand DNA Underlies In Vivo Hypermutability Induced by a Ubiquitous Envir...
Base Damage within Single-Strand DNA Underlies In Vivo Hypermutability Induced by a Ubiquitous Environmental Agent
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Chromosomal DNA must be in single-strand form for important transactions such as replication, transcription, and recombination to occur. The single-strand DNA (ssDNA) is more prone to damage than double-strand DNA (dsDNA), due to greater exposure of chemically reactive moieties in the nitrogenous bases. Thus, there can be agents that damage regions...
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Base Damage within Single-Strand DNA Underlies In Vivo Hypermutability Induced by a Ubiquitous Environmental Agent
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TN_cdi_plos_journals_1313535851
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313535851
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1553-7404,1553-7390
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1553-7404
DOI
10.1371/journal.pgen.1003149