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Interactions between glucocorticoid treatment and cis-regulatory polymorphisms contribute to cellula...

Interactions between glucocorticoid treatment and cis-regulatory polymorphisms contribute to cellula...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313546189

Interactions between glucocorticoid treatment and cis-regulatory polymorphisms contribute to cellular response phenotypes

About this item

Full title

Interactions between glucocorticoid treatment and cis-regulatory polymorphisms contribute to cellular response phenotypes

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2011-07, Vol.7 (7), p.e1002162

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Glucocorticoids (GCs) mediate physiological responses to environmental stress and are commonly used as pharmaceuticals. GCs act primarily through the GC receptor (GR, a transcription factor). Despite their clear biomedical importance, little is known about the genetic architecture of variation in GC response. Here we provide an initial assessment o...

Alternative Titles

Full title

Interactions between glucocorticoid treatment and cis-regulatory polymorphisms contribute to cellular response phenotypes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1313546189

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313546189

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1002162

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