An integration of genome-wide association study and gene expression profiling to prioritize the disc...
An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits
About this item
Full title
Author / Creator
Hsu, Yi-Hsiang , Zillikens, M Carola , Wilson, Scott G , Farber, Charles R , Demissie, Serkalem , Soranzo, Nicole , Bianchi, Estelle N , Grundberg, Elin , Liang, Liming , Richards, J Brent , Estrada, Karol , Zhou, Yanhua , van Nas, Atila , Moffatt, Miriam F , Zhai, Guangju , Hofman, Albert , van Meurs, Joyce B , Pols, Huibert A P , Price, Roger I , Nilsson, Olle , Pastinen, Tomi , Cupples, L Adrienne , Lusis, Aldons J , Schadt, Eric E , Ferrari, Serge , Uitterlinden, André G , Rivadeneira, Fernando , Spector, Timothy D , Karasik, David and Kiel, Douglas P
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Osteoporosis is a complex disorder and commonly leads to fractures in elderly persons. Genome-wide association studies (GWAS) have become an unbiased approach to identify variations in the genome that potentially affect health. However, the genetic variants identified so far only explain a small proportion of the heritability for complex traits. Du...
Alternative Titles
Full title
An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits
Authors, Artists and Contributors
Author / Creator
Zillikens, M Carola
Wilson, Scott G
Farber, Charles R
Demissie, Serkalem
Soranzo, Nicole
Bianchi, Estelle N
Grundberg, Elin
Liang, Liming
Richards, J Brent
Estrada, Karol
Zhou, Yanhua
van Nas, Atila
Moffatt, Miriam F
Zhai, Guangju
Hofman, Albert
van Meurs, Joyce B
Pols, Huibert A P
Price, Roger I
Nilsson, Olle
Pastinen, Tomi
Cupples, L Adrienne
Lusis, Aldons J
Schadt, Eric E
Ferrari, Serge
Uitterlinden, André G
Rivadeneira, Fernando
Spector, Timothy D
Karasik, David
Kiel, Douglas P
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1313586593
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313586593
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1000977
