Common genetic determinants of intraocular pressure and primary open-angle glaucoma
Common genetic determinants of intraocular pressure and primary open-angle glaucoma
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Author / Creator
van Koolwijk, Leonieke M E , Ramdas, Wishal D , Ikram, M Kamran , Jansonius, Nomdo M , Pasutto, Francesca , Hysi, Pirro G , Macgregor, Stuart , Janssen, Sarah F , Hewitt, Alex W , Viswanathan, Ananth C , ten Brink, Jacoline B , Hosseini, S Mohsen , Amin, Najaf , Despriet, Dominiek D G , Willemse-Assink, Jacqueline J M , Kramer, Rogier , Rivadeneira, Fernando , Struchalin, Maksim , Aulchenko, Yurii S , Weisschuh, Nicole , Zenkel, Matthias , Mardin, Christian Y , Gramer, Eugen , Welge-Lüssen, Ulrich , Montgomery, Grant W , Carbonaro, Francis , Young, Terri L , Bellenguez, Céline , McGuffin, Peter , Foster, Paul J , Topouzis, Fotis , Mitchell, Paul , Wang, Jie Jin , Wong, Tien Y , Czudowska, Monika A , Hofman, Albert , Uitterlinden, Andre G , Wolfs, Roger C W , de Jong, Paulus T V M , Oostra, Ben A , Paterson, Andrew D , Mackey, David A , Bergen, Arthur A B , Reis, André , Hammond, Christopher J , Vingerling, Johannes R , Lemij, Hans G , Klaver, Caroline C W , van Duijn, Cornelia M , Wellcome Trust Case Control Consortium 2 , DCCT/EDIC Research Group and The DCCT/EDIC Research Group
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Intraocular pressure (IOP) is a highly heritable risk factor for primary open-angle glaucoma and is the only target for current glaucoma therapy. The genetic factors which determine IOP are largely unknown. We performed a genome-wide association study for IOP in 11,972 participants from 4 independent population-based studies in The Netherlands. We...
Alternative Titles
Full title
Common genetic determinants of intraocular pressure and primary open-angle glaucoma
Authors, Artists and Contributors
Author / Creator
Ramdas, Wishal D
Ikram, M Kamran
Jansonius, Nomdo M
Pasutto, Francesca
Hysi, Pirro G
Macgregor, Stuart
Janssen, Sarah F
Hewitt, Alex W
Viswanathan, Ananth C
ten Brink, Jacoline B
Hosseini, S Mohsen
Amin, Najaf
Despriet, Dominiek D G
Willemse-Assink, Jacqueline J M
Kramer, Rogier
Rivadeneira, Fernando
Struchalin, Maksim
Aulchenko, Yurii S
Weisschuh, Nicole
Zenkel, Matthias
Mardin, Christian Y
Gramer, Eugen
Welge-Lüssen, Ulrich
Montgomery, Grant W
Carbonaro, Francis
Young, Terri L
Bellenguez, Céline
McGuffin, Peter
Foster, Paul J
Topouzis, Fotis
Mitchell, Paul
Wang, Jie Jin
Wong, Tien Y
Czudowska, Monika A
Hofman, Albert
Uitterlinden, Andre G
Wolfs, Roger C W
de Jong, Paulus T V M
Oostra, Ben A
Paterson, Andrew D
Mackey, David A
Bergen, Arthur A B
Reis, André
Hammond, Christopher J
Vingerling, Johannes R
Lemij, Hans G
Klaver, Caroline C W
van Duijn, Cornelia M
Wellcome Trust Case Control Consortium 2
DCCT/EDIC Research Group
The DCCT/EDIC Research Group
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Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1313592770
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313592770
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1002611
