Genome-Wide Assessment of AU-Rich Elements by the AREScore Algorithm
Genome-Wide Assessment of AU-Rich Elements by the AREScore Algorithm
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
In mammalian cells, AU-rich elements (AREs) are well known regulatory sequences located in the 3' untranslated region (UTR) of many short-lived mRNAs. AREs cause mRNAs to be degraded rapidly and thereby suppress gene expression at the posttranscriptional level. Based on the number of AUUUA pentamers, their proximity, and surrounding AU-rich regions...
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Full title
Genome-Wide Assessment of AU-Rich Elements by the AREScore Algorithm
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TN_cdi_plos_journals_1313612826
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313612826
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1002433
