Psoriasis patients are enriched for genetic variants that protect against HIV-1 disease
Psoriasis patients are enriched for genetic variants that protect against HIV-1 disease
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Author / Creator
Chen, Haoyan , Hayashi, Genki , Lai, Olivia Y , Dilthey, Alexander , Kuebler, Peter J , Wong, Tami V , Martin, Maureen P , Fernandez Vina, Marcelo A , McVean, Gil , Wabl, Matthias , Leslie, Kieron S , Maurer, Toby , Martin, Jeffrey N , Deeks, Steven G , Carrington, Mary , Bowcock, Anne M , Nixon, Douglas F and Liao, Wilson
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
An important paradigm in evolutionary genetics is that of a delicate balance between genetic variants that favorably boost host control of infection but which may unfavorably increase susceptibility to autoimmune disease. Here, we investigated whether patients with psoriasis, a common immune-mediated disease of the skin, are enriched for genetic va...
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Full title
Psoriasis patients are enriched for genetic variants that protect against HIV-1 disease
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TN_cdi_plos_journals_1313613381
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313613381
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1002514
