High-density SNP mapping of the HLA region identifies multiple independent susceptibility loci assoc...
High-density SNP mapping of the HLA region identifies multiple independent susceptibility loci associated with selective IgA deficiency
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Author / Creator
Ferreira, Ricardo C , Pan-Hammarström, Qiang , Graham, Robert R , Fontán, Gumersindo , Lee, Annette T , Ortmann, Ward , Wang, Ning , Urcelay, Elena , Fernández-Arquero, Miguel , Núñez, Concepción , Jorgensen, Gudmundur , Ludviksson, Björn R , Koskinen, Sinikka , Haimila, Katri , Padyukov, Leonid , Gregersen, Peter K , Hammarström, Lennart and Behrens, Timothy W
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Selective IgA deficiency (IgAD; serum IgA<0.07 g/l) is the most common form of human primary immune deficiency, affecting approximately 1∶600 individuals in populations of Northern European ancestry. The polygenic nature of IgAD is underscored by the recent identification of several new risk genes in a genome-wide association study. Among the chara...
Alternative Titles
Full title
High-density SNP mapping of the HLA region identifies multiple independent susceptibility loci associated with selective IgA deficiency
Authors, Artists and Contributors
Author / Creator
Pan-Hammarström, Qiang
Graham, Robert R
Fontán, Gumersindo
Lee, Annette T
Ortmann, Ward
Wang, Ning
Urcelay, Elena
Fernández-Arquero, Miguel
Núñez, Concepción
Jorgensen, Gudmundur
Ludviksson, Björn R
Koskinen, Sinikka
Haimila, Katri
Padyukov, Leonid
Gregersen, Peter K
Hammarström, Lennart
Behrens, Timothy W
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1313622906
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313622906
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1002476
